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Parent Category: Medicine
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Articles

Transcriptional Factors And Regulators

All the cellular processes in living cells such as growth, development, morphogenesis and cellular differentiation are a product of gene expression programs involving complicated transcriptional regulation of several genes. [ Read more ]

Folate Receptor 4 (FR4)

Folates play an important role in protein and nucleic acid biosynthesis and are particularly recognized for their roles in spinal canal and brain development during early pregnancy. [ Read more ]

Neuropilin-1/BDCA-4/CD304

Neuropilin-1 (Nrp-1) was recently identified as a possible surface marker for naturally occurring CD4+CD25+ regulatory T cells and is constitutively expressed on the cell irrespective of its activation status. [ Read more ]

A Functional Contributor to Cancer Metastatic Potential

Tumor metastasis plays a key role in assessing treatment strategies and an important factor in determining patient prognosis. Not surprisingly, significant effort has been focused on elucidating the molecular basis behind tumor metastasis. [ Read more ]

In Search of Putative FOXP3+ Cell Surface Markers

Flow cytometric analysis of intracellular FOXP3 (IMG-5802D) and cell surface FR4 with clone 12A5 (IMG-6217C) (left) and clone TH6 (IMG-6218C) (right) at 0.06 ug/10^6 mouse splenocytes. [ Read more ]

TLR10- cluster of differentiation 290

Toll-like receptor 10 (TLR10) often known as CD290 (cluster of differentiation 290), is the most recently identified human homolog of the Drosophila TOLL protein. [ Read more ]

TLR9- cluster of differentiation 289

Toll-like receptor 9 (TLR9) often known as CD289 (cluster of differentiation 289), is a member of the Toll-like receptor family that recognizes pathogen-associated molecular pattern. [ Read more ]

TLR8- cluster of differentiation 288

Toll-like receptor 8 (TLR8) often designated as CD288 (cluster of differentiation 288) is a member of evolutionarily conserved Toll-like receptor family which are critical parts of the evolutionarily conserved innate immune system. [ Read more ]

TLR7- cluster of differentiation 287

Toll-like receptor 7 (TLR7), is an immune gene possessed by humans, other mammals and additionally in avian species playing a significant role in initiating antiviral immune responses. [ Read more ]

TLR6- cluster of differentiation 286

Toll-like receptor 6 (TLR6) often designated as CD286 (cluster of differentiation 286), is a member of the Toll-like receptor family, a highly conserved series of ancient innate immune pattern recognition receptors. [ Read more ]

TLR5- cluster of differentiation 285

Toll-like receptor 5 (TLR5), a member of the evolutionarily conserved Toll-like receptor family, has evolved to permit mammals specifically to detect flagellated bacterial pathogens. [ Read more ]

TLR4- cluster of differentiation 284

Toll-like receptor 4 (TLR4) often designated as CD284 (cluster of differentiation 284) is a class I transmembrane receptor belonging to the large homologous family of Toll like receptors. [ Read more ]

TLR3- cluster of differentiation 283

Toll-like receptor 3 (TLR3) often designated as CD283 (cluster of differentiation 283) is a type I transmembrane receptor protein. [ Read more ]

TLR2- cluster of differentiation 282

Toll-like receptor 2 (TLR2), often designated as CD282 (cluster of differentiation 282) is a type I transmembrane protein belonging to the large homologous family of Toll like receptors. [ Read more ]

Poison Ivy Season Is Here

Summer can be scary. Especially if you are prone to poison ivy skin rash! Your regular walk in the woods can quickly turn into a nightmarish experience if you are not careful. [ Read more ]

How To Succeed At Your Medical School Interview

Medical school interviews can be a standard panel interview, blinded interview, which is not so common then partially blinded interview and open interview. [ Read more ]

Two Aspects of the Debate on Pharmaceutical Patents Still Enforced

Latin America has made great strides in protecting pharmaceutical patents still held by the intellectual property holders. Through free trade agreements such as NAFTA as well as some decisions made by South American governments, particularly Brazil, [ Read more ]

A Look at Compulsory Licensing & Essential Medicines in the Pharmaceutical Industry

Compulsory licensing of essential medicines doesn’t always provide the greatest help to the poorest people of the world according to a round table highlighted by The Policy Network. The danger of compulsory licensing is that it can [ Read more ]

Drug Patents Are Important

Protecting drug patents is an important effort in the global fight against disease. By protecting drug patents, the creators of these drugs can obtain a window to recoup the massive financial investment of creating a new medication. Without that oppo [ Read more ]